Ginsenoside Rg3 Inhibits Cells Viability and Promotes Apoptosis of Oesophageal Cancer Cells via Downregulating the Phosphatidylinositol 3 Kinase-Protein Kinase B Signalling Pathway

نویسندگان

چکیده

Although ginsenoside Rg3 has been shown to exert anticancer effects on a variety of malignancies, the and molecular mechanisms oesophageal cancer remain unclear. Therefore, these factors must be explored. Here, we analyzed effect cell proliferation migration, as well its apoptosis. Furthermore, detected downstream pathways that could act on. The results showed significantly inhibited migration promoted We found regulates phosphatidylinositol-3-kinase/protein kinase B/mammalian target rapamycin pathway in development. In general, inhibits cells via induction apoptosis down regulation pathway. This study aimed suggest new treatment options for cancer.

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ژورنال

عنوان ژورنال: Indian Journal of Pharmaceutical Sciences

سال: 2022

ISSN: ['0250-474X', '1998-3743']

DOI: https://doi.org/10.36468/pharmaceutical-sciences.spl.475